Dr. Annett Halle

Microglial cells are cells of the innate immune system in the brain and act as the first form of immune defense in the central nervous system. Furthermore, microglial cells are key players in brain maintenance by constantly interacting with neurons and synapses and acting as scavenger cells.
Microglial cells play an important role in the initiation and progression of Alzheimer’s disease.
We are interested in the molecular mechanisms that shape microglial behavior under physiological conditions and in Alzheimer’s disease.