Professor Dr. Günter Mayer

Life & Medical Sciences Institute (LIMES)
Chemical Biology & Medicinal Chemistry Unit
Gerhard-Domagk-Str. 1
D- 53121 Bonn

Phone +49  (0) 228 73-4808
Fax +49  (0) 228 73-4809
gmayer@uni-bonn.de

Website Mayer Group
Website LIMES

Curriculum vitae Professor Dr. Günter Mayer

Research interest

We are developing molecular tools for the functional analysis biological processes as well as for the development of novel diagnostic and therapeutic strategies. Our scientific work is assigned to the fields of microbiology, cancer, hematology, and photochemistry.

Techniques

We are using combinatorial and chemical biology approaches to identify target specific ligands based on nucleic acids and small organic molecules.

5 most important publications

1. Tesmer VM, Lennarz S, Mayer G, Tesmer JJ. (2012) Molecular mechanism for inhibition of G protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure, 20: 1300-1309.

2. Müller J, Becher T, Braunstein J, Berdel P, Gravius S, Rohrbach F, Oldenburg J, Mayer G, Pötzsch B. (2011) Profiling of Active Thrombin in Human Blood by Supramolecular Complexes Angew. Chem Int Ed 50: 6076-6078.

3. Raddatz MS, Dolf A, Endl E, Knolle P, Famulok M, Mayer G. (2008) Enrichment of cell-targeting and population-specific aptamers by fluorescence-activated cell sorting. Angew. Chem Int Ed, 47: 5190-5193.

4. Heckel A, Buff MC, Raddatz MS, Müller J, Pötzsch B, Mayer G. (2006) An anticoagulant with light-triggered antidote activity. Angew Chem Int Ed, 45: 6748-6750.

5. Heckel A, Mayer G. (2005) Light-regulated aptamer: An anti-thrombin aptamer with caged thymidine nucleobases. J Am Chem Soc, 127: 822-823.