We are interested in the neurobiology of perception and memory. We explore neuronal behavior in the medial temporal lobe to understand how conscious percepts are transferred into episodic memory traces.
We investigate the pathophysiological mechanisms that lead to the occurence of epileptic seizures. Our particular focus is on microscopic phenomena such as high frequency oscillations, microseizures, cellular and network behavior.
We record in vivo from single neurons in the medial temporal lobes of epilepsy patients undergoing monitoring for resective surgery. Our electrophysiological paradigms are occasionally complemented by fMRI, EEG, or psychophysics experiments. Our analyses of discrete spike trains and continuous field potentials require techniques from linear and nonlinear time series analysis.
5 most important publications
1. Kreuz T, Chicharro D, Houghton C, Andrzejak RG, Mormann F. (2013) Monitoring spike train
synchrony. J Neurophysiol, 109: 1457-72.
2. Mormann F, Dubois J, Kornblith S, Milosavljevic M, Cerf M, Ison M, Tsuchiya N, Kraskov A, Quiroga
RQ, Adolphs R, Fried I, Koch C. (2011) A category-specific response to animals in the right human
amygdala. Nat Neurosci, 14: 1247-1249.
3. Cerf M, Thiruvengadam N, Mormann F, Kraskov A, Quiroga RQ, Koch C, Fried I. (2010) On-line,
voluntary control of human temporal lobe neurons. Nature, 467: 1104-1108.
4. Mormann F, Kornblith S, Quiroga RQ, Kraskov A, Cerf M, Fried I, Koch C. (2008) Latency and
selectivity of single neurons indicate hierarchical processing in the human medial temporal lobe. J
Neurosci, 28: 8865-8872.
5. Mormann F, Andrzejak RG, Elger CE, Lehnertz K. (2007) Seizure prediction: the long and
winding road. Brain, 130: 314-333.