Group Leader, Cellular Mechanism of Cognition
Institute of Experimental Epileptology and Cognition Research
University of Bonn Medical Center | Life & Brain Center
D- 53175 Bonn
Phone +49 (0) 228 6885-157
Curriculum vitae PhD Laura Ewell
We strive to understand how the unique properties of individual neurons support complex behaviors and pathology. We study the hippocampus, a brain structure crucial for memory and also strikingly vulnerable to pathologies.
We use in vitro electrophysiology to study individual neurons and microcircuits and in vivo electrophysiology to study networks during behavior.
5 most important publications
1. Ewell LA. (2017) Assessing Levels of Awareness During Seizures in Animal Models. Epilepsy Curr., 17(6): 372-373.
2. Ewell LA. (2017) To sleep perchance to spike: a functional role for dentate spikes in memory. J. Physiol., 595(14) :4565.
3. Madar A*, Ewell, LA*, Jones MV. (2017) Pattern separation of spiketrains by individual granule cells of the dentate gyrus. Preprinted at bioRxiv 107706; doi: https://doi.org/10.1101/107706.
4. Lippi G, Fernandes CC, Ewell LA, Romoli B, Curia G, Taylor SR, Frady EP, Jensen AB, Liu JC, Chaabane MM, Belal C, Nathanson JL, Zoli M, Leutgeb JK, Biagini G, Yeo GW, Berg, DK. (2016) MicroRNA – 101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks. Neuron, 92(6): 1337-1351.
5. Ewell LA, Liang L, Armstrong C, Soltesz I, Leutgeb S, Leutgeb JK. (2015) Brain state is a major factor in pre-seizure hippocampal network activity and influences success of seizure intervention. J. Neurosci., 35(47): 15635-15648.