Dr. Wolf Maximilian Harmening

Advanced adaptive optics for single-cell psychophysics
University Eye Hospital Bonn
Building 05, Room UG/1
Ernst-Abbe-Str. 2, 53127 Bonn

Phone +49  (0) 228 287-15882 (or 19818)


Curriculum vitae Dr.Wolf Maximilian Harmening

Research Interests

Optical, physiological and perceptual characteristics of human and animal vision. We use adaptive optics imaging techniques to create high resolution images of the living human retina. By means of fast optical light switching and real-time compensation for retinal motion, we are able to target and stimulate individual photoreceptor cells for extremely precise visual function testing.


adaptive optics, high-resolution retinal imaging, visual psychophysics, behavioral testing

5 most important publications

1. Domdei N*, Domdei L*, Reiniger J, Linden M, Holz FG, Roorda A, Harmening WM. (2018) Ultra-high contrast retinal display system for single photoreceptor psychophysics. Biomedical Optics Express, 9: 157-172.

2.  Fang PP, Domdei N, Herrmann P, Schmitz-Valckenberg S, Holz FG, Harmening WM, Krohne TU. (2017) Minimal optical coherence tomography B-scan density for reliable detection of intra- and subretinal fluid in patients with macular diseases. Retina, DOI 10.1097/IAE.0000000000001918.

3. Birtel J, Harmening WM, Krohne TU, Holz FG, Issa P, Herrmann P. (2017) Retinal injury following laser pointer exposure—a systematic review and case series. Deutsches Ärzteblatt International. 114: 831-837.

4. Tuten WS*, Harmening WM*, Sabesan R, Roorda A, Sincich LC. (2017) Spatiochromatic interactions between individual cone photoreceptors in the human retina. The Journal of  Neuroscience, 37(39): 9498-9509.

5. Pfau M, Lindner M, Mueller, PL, Birtel J, Finger RP, Harmening WM, Fleckenstein M, Holz FG, Schmitz-Valckenberg S. (2017) Effective dynamic range and retest-reliability of two-color scotopic fundus-controlled perimetry using the S-MAIA in patients with macular diseases. Investigative Ophthalmology & Visual Science, DOI 10.1167/iovs.17-21454.